THE NARDOO Creek this evening is rising at Wedderburn for the third time in less than a fortnight as the region spent weekend preparing for preparing for a rain bomb that could dump up to 200mm on the Loddon in 48 hours.

Community working bees, CFA volunteers and SES crews from Melbourne were part of sandbagging efforts in Wedderburn and Korong Vale from Saturday afternoon. Hundreds of bags were taken by residents, some bracing for the third flood since Christmas Day while deliveries were also made by CFA members to Borung and residents in local towns.

Some residents in the vicinity of Wallaby Way sandbagged their homes this morning and then left for safer ground in town.

Rainfall was steady across the region from 7am with heavy falls in Pyramid Hill where more than 100mm saw flooding that forced closure of the Victoria Hotel for the day. Similar falls were recorded at Mitiamo and Prairie were sections of road flooded for the first time, according to local residents.

Multiple roads are cut. Although the VicTraffic website has not been updated, the Inglewood-Arnold Road is closed and there are warnings for other roads in the district including on the Borung Road between Fernihurst and Bears Lagoon while sections of the Calder Highway near Marong have also become impassable late evening while water is rising across the highway between Glenalbyn and Wedderburn. The Wedderburn-Korong Vale Road is also currently closed.

And water has made the Raywood-Mitiamo Road impassable this evening, said residents.

SES and police were responding to an incident on between Wedderburn and Korong Vale this evening.

The wait for water to flow down the Nardoo Creek was longer than floods on Christmas Day and last Tuesday. Water spewed over the Tantalla Street culvert about 6pm.

Within 30 minutes, resident Irene Finch said: "Water now across Racecourse Road/Korong Vale Road. It come up quite quickly."

SES crews from Footscray, Hoopers Crossing, Craigieburn and Whittlesea arrived in Wedderburn about 1pm to open a local incident centre. They joined CFA volunteers in assessing projected flood levels around the town.

There was also assessment of trees likely to fall, some barely in the ground after earlier flooding washed away up to a metre of soil.

Flood warnings remain in place for the Loddon River with rain predicted to continue into tomorrow.